With the expertise brought together in MACRAMÉ and the experiences gained throughout the project duration, MACRAMÉ responded to the call for evidence to the Advanced Materials Act.
MACRAMÉ colleagues from EMPA contributed to the publication ‘Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho-Epithelial Cells by Modulating Eicosanoid Lipid Signaling’. For the successful commercial development of emerging 2D materials, it is crucial to understand their potential biological effects on healthy and diseased individuals.
MACRAMÉ Experts used the opportunity to provide feedback in the commenting phase of the revision of the Safe and Sustainable by Design Chemicals and Materials Framework.
The ‘Joint Risk Assessor Summit on Advancing Safety & Sustainability Assessments of Advanced Materials’ hosted by ACCORDs, iCARE, MACRAMÉ, and nanoPASS, was a full success. To address new challenges for safety and sustainability assessment coming with advanced materials, the EU Horizon Europe projects ACCORDs, iCARE, MACRAMÉ, and nanoPASS hosted the Read more
The development of new approach methodologies (NAMs) to replace current in vivo testing for the safety assessment of engineered nanomaterials (ENMs) is hindered by the scarcity of validated experimental data for many ENMs. MACRAMÉ partners contributed to the publication ‘Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials’.
MACRAMÉ colleagues from EMPA have published a study on Data-Driven Prediction of Nanoparticle Biodistribution from Physicochemical Descriptors.
MACRAMÉ colleagues from EMPA and Epithelix have published a paper entitled ‘Silicon Carbide Nanowires Impair Mucociliary Clearance-Mediated Innate Immunity in Primary Human Bronchial Epithelial Cells’. In this study, the fate of zero-dimensional, one-dimensional, and two-dimensional silicon- and carbon-based nanomaterials was investigated for the first time.
Colleagues from the MACRAMÉ Partner University Birmingham contributed to a new review paper. The study conducts an exhaustive analysis of the state-of-the-art developments in the creation and enhancement of MXene-based membranes. Membranes have become a basis in tackling the global challenge of freshwater scarcity, notably in the fields of desalination and water purification.
MACRAMÉ Partner EMPA published a paper with the title ‘Bridging the gap: Innovative human-based in vitro approaches for nanomaterials hazard assessment and their role in safe and sustainable by design, risk assessment, and life cycle assessment’. The application of nanomaterials in industry and consumer products is growing exponentially, which has pressed the development and use of predictive human in vitro models in pre-clinical analysis to closely extrapolate potential toxic effects in vivo.
The new publication entitled ‘Roadmap towards safe and sustainable advanced and innovative materials. (Outlook for 2024-2030)’ has been co-authored by a team of researchers from the MACRAMÉ Project Partners AcumenIST, Seven Past Nine GmbH, Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Rijksinstituut voor Volksgezondheid en Milieu, and TEMAS Solutions GmbH. The publication Read more
