MACRAMÉ colleagues from BAuA and IBE together with experts from the German BfR have published an extensive study on the behaviour of Macrophages when they encounter fibres.
MACRAMÉ Project Partners AcumenIST have published an article about the discussions and conclusions of a workshop that elucidated how Artificial Intelligence (AI) is increasingly influencing chemical risk assessment, enabling faster, more comprehensive, and potentially more ethical assessments.
MACRAMÉ colleagues from EMPA contributed to the publication ‘Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho-Epithelial Cells by Modulating Eicosanoid Lipid Signaling’. For the successful commercial development of emerging 2D materials, it is crucial to understand their potential biological effects on healthy and diseased individuals.
The development of new approach methodologies (NAMs) to replace current in vivo testing for the safety assessment of engineered nanomaterials (ENMs) is hindered by the scarcity of validated experimental data for many ENMs. MACRAMÉ partners contributed to the publication ‘Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials’.
MACRAMÉ colleagues from EMPA have published a study on Data-Driven Prediction of Nanoparticle Biodistribution from Physicochemical Descriptors.
MACRAMÉ colleagues from EMPA and Epithelix have published a paper entitled ‘Silicon Carbide Nanowires Impair Mucociliary Clearance-Mediated Innate Immunity in Primary Human Bronchial Epithelial Cells’. In this study, the fate of zero-dimensional, one-dimensional, and two-dimensional silicon- and carbon-based nanomaterials was investigated for the first time.
The MACRAMÉ Project team has published an Innovation Report about its Project’s R&I approach. In the paper entitled ‘MACRAMÉ – Advanced characterisation methodologies to assess and predict the health and environmental risks of advanced materials‘, the authors describe the planned information-flow between the different R&I activities conducted in the Project (see Read more
Colleagues from the MACRAMÉ Partner University Birmingham contributed to a new review paper. The study conducts an exhaustive analysis of the state-of-the-art developments in the creation and enhancement of MXene-based membranes. Membranes have become a basis in tackling the global challenge of freshwater scarcity, notably in the fields of desalination and water purification.
MACRAMÉ Partner EMPA published a paper with the title ‘Bridging the gap: Innovative human-based in vitro approaches for nanomaterials hazard assessment and their role in safe and sustainable by design, risk assessment, and life cycle assessment’. The application of nanomaterials in industry and consumer products is growing exponentially, which has pressed the development and use of predictive human in vitro models in pre-clinical analysis to closely extrapolate potential toxic effects in vivo.
In its Report on Stakeholder Involvement & Knowledge Transfer in the first 18 Months, the MACRAMÉ Project provides an overview of the stakeholder engagement and knowledge transfer on harmonisation and standardisation (H&S) activities for advanced materials undertaken in the first 18 months. The Project organised and conducted a number of Read more
